Chromatin domains and territories: flexibly rigidстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:The nucleus is a highly organized solid-state system, rigid and flexible at the same time, where enzymes are organized in complex processing factories. This is achieved by the organization of nuclear DNA into territories and domains, which allow compartmentalization and compaction without sacrificing accessibility. The present review discusses the implications of the organization of chromosomal domains and territories in development and carcinogenesis.