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Formation of the multifunctional metal-polymer composite with antiseptic, anesthetic and bactericidal properties by green technologiesстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 5 декабря 2018 г.
- Авторы: Said-Galiev E.E., Rubina M.S., Vasil’kov A.Yu, Naumkin A.V., Khokhlov A.R., Abd-Elsalam K.A.
- Журнал: AIP Conference Proceedings
- Том: 1981
- Номер: 020159
- Год издания: 2018
- Первая страница: 1
- Последняя страница: 4
- DOI: 10.1063/1.5046021
- Аннотация: The preparation technique for multifunctional metal-polymer composites based on the commercial medical sponge Collachit-G with antiseptic, anesthetic and bactericidal properties has been developed. The immobilization of ibuprofen and silver nanoparticles on/into polymer was achieved by using combination of two green technologies: the treatment in supercritical carbon dioxide and metal vapor synthesis. The composites were investigated by XRFA, TEM and XPS. A drug- release process and its mechanism have been studied within the framework of the Ritger-Peppas model. It was found that ibuprofen content in the sponge reaches 51 % from its weight. The average linear size of silver particles is 6 ± 1nm, and silver atoms are in non-oxidized state. Duration of ibuprofen escape from initial sponge in the phosphate buffer with pH =7.4 is 3 hours. Diffusion obeys to Fick’s law. The presence of Ag clusters in the sponge does not principally change the diffusion mechanism.
- Добавил в систему: Саид-Галиев Эрнест Ефимович
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