ИСТИНА

Semiconductor and plasmonic nanoparticles (NPs) exhibit unique op-tical properties, which are promising for different biomedical applica-tions. Silicon (Si) NPs (Si-NPs) are especially interesting because they are biocompatible, biodegradable and can be easily prepared by chemi-cal and laser-assisted methods [1,2]. Surface passivated nanocrystalline Si-NPs exhibit the photoluminescence (PL) and Raman scattering, which can be used for optical bioimaging and other biophotonic applications as photodynamic and photothermal therapy [1]. The linear and nonlinear optical spectroscopy are used to monitor Si-NPs in biosystems [3]. Si-NPs in aqueous media act as an efficient absorber of light in the visible and near-infrared spectral regions and it is promising for photohyper-thermia applications [4]. Si-NPs with impurities and intrinsic electronic states can act as labels in magnetic resonance imaging [5], which is widely used in the diagnosis of cancer. Halloysite nanotubes (HNTs) with immobilized plasmonic (gold and silver) NPs are explored as poten-tial nano-templates for surface-enhanced Raman scattering (SERS) for biosensorics and biophotonics [6]. HNTs with immobilized gold NPs are found to sensitize the photohyperthermia under continuous wave and nanosecond pulsed laser excitation with a photon energy close to the plasmonic resonance. These physical properties of semiconductor and plasmonic NPs are promising for the so-called theranostics (combination of therapy and diagnostics). [1] V.Yu. Timoshenko, in “Handbook of Porous Silicon”, Ed. L.Canham, Springer Publ., pp. 1461-1469 (2018). [2] A.V. Kabashin, V. Yu. Timoshenko, Nanomedicine 11, 2247 (2016). [3] A.Yu. Kharin et al., Adv. Opt. Mat. 1801728 (2019). [4] V.A. Oleshchenko et al., Appl. Surf. Sci. 145661 (2020). [5] V.M. Fomin, V.Yu. Timoshenko, Appl. Sci. 10 (14), 4992 (2020). [6] A.V. Kornilova et al., Appl. Sci. 11 (10), 4565 (2020). [7] A.V. Kornilova et al., Appl. Surf. Sci. 566, 150671 (2021).