ИСТИНА

We have performed computer simulation of three-component systems consisting of lecithin, bile salt and solvent, which may be water or an organic solvent, and studied the structure of molecular aggregates. We found that formation of "worm-like" micelles is observed in hexane-lecithin solution with increasing bile salt concentration. Addition of bile salts into the aqueous lecithin solution also induces formation of elongated structures with ellipsoidal or cylindrical shape. Aggregates morphology in lecithin - bile salts mixture could be affected by inorganic salt. We believe that the formation of long flexible worm-like micelles can be the reason for the experimentally observed viscosity increase.