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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Amine Adducts of Triallylborane As Highly Reactive Allylborating Agents For Cu(I)-Catalyzed Allylation of Chiral Sulfinyliminesстатья
- Авторы: Alexeev Michael S., Strelkova Tatyana V., Ilyin Michail M.
- Журнал: Organic and Biomolecular Chemistry
- Том: 22
- Год издания: 2024
- Издательство: Royal Society of Chemistry
- Местоположение издательства: United Kingdom
- Аннотация: The implementation of selective catalytic processes with highly active reagents is an attractive strategy that meets modern principles of sustainable development of chemistry. In the current study, we for the first time described method and general principles of Cu(I)-catalyzed allylation of imines with allylic triorganoboranes. Triallylborane is an extremely reactive compound and cannot be used for the catalytic allylation of imines, whereas its amine adducts are ideal substrates for catalysis. A structure of amine fragment successfully balances the safety, selectivity and stability of the allylboron reagent, allowing it to demonstrate high activity in catalytic allylation reactions, exceeding many times any known allylboranes. The obtained results supported by quantitative kinetics data and DFT calculations. Catalysis efficacy of the system was demonstrated on the model sulfinylimines. Taking into account high reactivity and unsurpassed atom-economy of amine adducts of triallylborane (AAT), they can be considered as prospective allylation reagents with Cu(I) and other appropriate metallocatalysts